Oxidative-stress-mediated arterial dysfunction in patients with peripheral arterial disease
نویسندگان
چکیده
منابع مشابه
Prevalence of Peripheral Arterial Disease in Diabetic Patients
Objective: Peripheral Arterial Disease (PAD) is a state characterized by atherosclerotic occlusive disease of lower extremities. Diabetes is the main risk factor for PAD. Material and Methods: To assess the prevalence of PAD, a cross sectional study was performed on 352 diabetic patients who referred to Yazd diabetes research center from 2007 to 2010. Vascular assessment was done by measuring ...
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Objective. Endothelial dysfunction plays a key role in atherosclerotic disease. Several methods have been reported to be useful for evaluating the endothelial dysfunction, and we investigated the endothelial dysfunction in patients with peripheral arterial disease (PAD) using peripheral arterial tonometry (PAT) test in this study. Furthermore, we examined the factors significantly correlated wi...
متن کاملlower extremity arterial calcification as a predictor of coronary atherosclerosis in patients with peripheral arterial disease
conclusion peripheral arterial calcification is significantly correlated with cad extent in patients with pad. peripheral arterial calcification can be a useful marker for predicting multivessel-cad. results lecs in multivessel-cad were significantly higher than those in nonsignificant cad (10.0 ± 5.8 versus 4.0 ± 3.1, p < 0.001). lecs significantly correlated with ccs (r = 0.831, p < 0.001) an...
متن کاملPeripheral arterial disease in patients with diabetes.
Peripheral arterial disease (PAD) is a chronic, lifestyle-limiting disease and is an independent predictor of cardiovascular and cerebrovascular ischemic events. Despite the recognition that PAD is associated with a marked increase in the risk of ischemic events, this particular manifestation of systemic atherosclerosis is largely underdiagnosed and undertreated. The risk of PAD is markedly inc...
متن کاملEndothelial dysfunction and peripheral arterial disease.
We read with interest the study of Loffredo et al. investigating the association of oxi-dative stress and endothelial function in patients with peripheral arterial disease (PAD). The authors demonstrated that flow-mediated vasodilation (FMD) of the brachial artery was significantly lower in patients with PAD compared with controls, whereas 8-hydroxy-2-deoxy-2-deoxyguanosine (a marker of oxidati...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2006
ISSN: 0195-668X,1522-9645
DOI: 10.1093/eurheartj/ehl533